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AN ANTIOXIDANT POTENTIAL OF HYDROMETHANOLIC EXTRACT OF URTICA
PARVIFLORA ROXB.
Savita Pandey1 Sangeeta Pilkhwal Sah1*,
Mukesh Lal Sah1, and Devendra Mishra2
1 Department of Pharmaceutical Sciences Bhimtal
Campus, Kumaon University, Nainital, Uttarakhand
2 Department of Applied Chemistry Birla Institute of Applied Sciences
Bhimtal Nainital Uttarakhand–263136
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Date of Web Publication
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15-Aug-2010
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*Correspondence Author: E-mail: spilkhwal@yahoo.com
ABSTRACT
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Antioxidant activity of hydromethanolic extract of Urtica parviflora Roxb.
(family Urticaceae) was investigated by different in vitro methods, namely,
nitric oxide scavenging, DPPH scavenging, and reducing power assay. In the present
study, plant extract exhibited dose dependent free radical scavenging and reducing
activity. The antioxidant activity of the hydromethanolic extract of Urtica parviflora
Roxb. was compared with ascorbic acid as standard. In addition, phytochemical screening
of hydromethanolic extract of the plant was undertaken to identify the phytochemicals
present in the extract. Phytochemical examination revealed the presence of alkaloids,
polysaccharides, saponins, flavonoids, phenolic compounds, glycosides and tannins.
It was concluded that the extract contains important phytoconstituents responsible
for antioxidant effect. The study indicated that Urtica parviflora could
protect the cell injury caused by the reactive oxygen species and might be a valuable
source of antioxidant both for medicine and food industry.
KEYWORDS Urtica parviflora, flavonoid, salkaloids, DPPH scavenging, reducing
power
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