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CHEMICAL COMPOSITION AND ANTIMICROBIAL ACTIVITY OF SOLIDAGO
CANADENSIS LINN. ROOT ESSENTIAL OIL
Devendra Mishra1*, Shivani Joshi2,
Ganga Bisht2, and Sangeeta Pilkhwal3
1 Department of Applied Chemistry, Birla Institute
of Applied Sciences Bhimtal, Nainital, India
2 Department of Chemistry, Kumaun University, Nainital, India
3 Department of Pharmaceutical Sciences, Bhimtal Campus, Kumaun
University, Nainital, India
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Date of Web Publication
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15-Aug-2010
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*Correspondence Author: E-mail: mishra.d123@gmail.com
 ABSTRACT
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The essential oil from the roots of Solidago canadensis Linn. (fam. Asteraceae)
was analyzed by GC, GC/MS and NMR spectroscopy. 39 constituents comprising 75.4%
of the total oil were identified from the oil. Thymol constituted 20.25% of the
oil followed by α-copaene (6.26%) and carvacrol (5.51%).The antimicrobial
activity of the oil was evaluated using disc diffusion method. Results showed that
the oil exhibited significant antibacterial activity against S. feacalis
and E. coli whereas it showed moderate antifungal activity against C. albicans.
KEYWORDS: Solidago canadensis, essential oil, thymol, antimicrobial activity,
disc diffusion.
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